What was the effect of increasing population size of time to fixation
When we ran the test with the population at 10, it happened far quicker than when there were 200 beings in the population.However, based on the slopes of the regression lines the results also suggest that the rate of preferential of fixation of at→gc.While the above results holds in the limit of large population size, we present a small directed graph that is a suppressor and has a slightly shorter fixation time than the complete graph for the same population size (see supplementary note 1, section 3.1).In small populations, allele fixation is more powerful than in large populations.And the effective population size (ne), which also depends on f and the variance of family size.
The increase in fixation probability occurs because in a growing population individuals carrying the mutant allele are more likely to have offspring.An increase in population as well increases the fixation time of allele a and a.Effects of partial inbreeding on fixation rates and variation of mutant genes.Ne = n/(1 + f), and the time until fixation is approximately equal to ne/n times the time to fixation with random mating, but this relation does not hold, however.The founder effect occurs when few individuals from a larger population establish a new population and also decreases the genetic diversity, and was originally outlined by ernst mayr.
It is found that gene conversion has an effect to increase the effective population size, so that weak selection works more efficiently in a multigene family.These results suggest a preferential fixation of at→gc over gc → at mutations over time.Ability has to tend to 0 as the population size n grows large.Due to this founder effect, the ancestral population size is expected to decline with increasing distance from africa.